Cargando…

Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice

Primary sclerosing cholangitis (PSC) is a cholestatic liver disease of unknown etiopathogenesis characterized by fibrous cholangiopathy of large and small bile ducts. Systemic administration of a murine TNF-related apoptosis-inducing ligand (TRAIL) receptor agonist induces a sclerosing cholangitis i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guicciardi, Maria Eugenia, Krishnan, Anuradha, Bronk, Steven F, Hirsova, Petra, Griffith, Thomas S, Gores, Gregory J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386369/ https://www.ncbi.nlm.nih.gov/pubmed/28055006 http://dx.doi.org/10.1038/cddis.2016.459

Ejemplares similares

TRAIL deletion prevents liver inflammation but not adipose tissue inflammation during murine diet‐induced obesity
por: Hirsova, Petra, et al.
Publicado: (2017)

Vismodegib Suppresses TRAIL-mediated Liver Injury in a Mouse Model of Nonalcoholic Steatohepatitis
por: Hirsova, Petra, et al.
Publicado: (2013)

IL-17 Signaling in Primary Sclerosing Cholangitis Patient-Derived Organoids
por: Garcia Moreno, Ana Sofia, et al.
Publicado: (2023)

Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis
por: Sarcognato, Samantha, et al.
Publicado: (2021)

Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib
por: Lecis, D, et al.
Publicado: (2010)

Overlap Syndrome between Primary Biliary Cholangitis and Primary Sclerosing Cholangitis
por: Sundaram, Sridhar, et al.
Publicado: (2018)

Evaluation of Biliary Calprotectin as a Biomarker in Primary Sclerosing Cholangitis
por: Gauss, Annika, et al.
Publicado: (2016)

Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines
por: Koch, Annkathrin, et al.
Publicado: (2021)

Follicular T Helper Cell Signatures in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis
por: Adam, Leonie, et al.
Publicado: (2018)

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: Current Knowledge of Pathogenesis and Therapeutics
por: Park, Ji-Won, et al.
Publicado: (2022)

Potential Role of Inflammation-Promoting Biliary Microbiome in Primary Sclerosing Cholangitis and Cholangiocarcinoma
por: Miyabe, Katsuyuki, et al.
Publicado: (2022)

Induction of Breast Cancer Cell Apoptosis by TRAIL and Smac Mimetics: Involvement of RIP1 and cFLIP
por: Holmgren, Christian, et al.
Publicado: (2022)

Future Therapeutic Directions for Smac-Mimetics
por: Morrish, Emma, et al.
Publicado: (2020)

Cellular Inhibitor of Apoptosis (cIAP)-Mediated Ubiquitination of Phosphofurin Acidic Cluster Sorting Protein 2 (PACS-2) Negatively Regulates Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Cytotoxicity
por: Guicciardi, Maria Eugenia, et al.
Publicado: (2014)

Diagnosing Biliary Strictures: Distinguishing IgG4-Related Sclerosing Cholangitis From Cholangiocarcinoma and Primary Sclerosing Cholangitis
por: Hori, Yasuki, et al.
Publicado: (2021)

Overlap syndrome of primary biliary cholangitis and primary sclerosing cholangitis: two case reports
por: Yacoub, Haythem, et al.
Publicado: (2023)

Current Concepts in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis
por: Sclair, Seth N, et al.
Publicado: (2015)

Biliary endoscopy in the management of primary sclerosing cholangitis and its complications
por: Fung, Brian M., et al.
Publicado: (2019)

The Role of Microbiota in Primary Sclerosing Cholangitis and Related Biliary Malignancies
por: Özdirik, Burcin, et al.
Publicado: (2021)

Induction of interferon-β and interferon signaling by TRAIL and Smac mimetics via caspase-8 in breast cancer cells
por: Granqvist, Victoria, et al.
Publicado: (2021)

Secondary sclerosing cholangitis: mimics of primary sclerosing cholangitis
por: Ludwig, Daniel R., et al.
Publicado: (2022)

New light on Smac mimetics and breast cancer
por: Cornmark, L, et al.
Publicado: (2016)

Hyperosmotic stress enhances cytotoxicity of SMAC mimetics
por: Bittner, Sebastian, et al.
Publicado: (2017)

SMAC Mimetics as Therapeutic Agents in HIV Infection
por: Molyer, Bengisu, et al.
Publicado: (2021)

A Systematic Review of Patient‐Reported Outcomes in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis
por: Kim, Hannah P., et al.
Publicado: (2020)

A patient with primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis variant syndrome
por: Terziroli Beretta-Piccoli, Benedetta, et al.
Publicado: (2019)

Geo-epidemiology and environmental co-variate mapping of primary biliary cholangitis and primary sclerosing cholangitis
por: Dyson, Jessica Katharine, et al.
Publicado: (2020)

Quaternary Benzophenanthridine Alkaloids Act as Smac Mimetics and Overcome Resistance to Apoptosis
por: Kulíšková, Petra, et al.
Publicado: (2023)

EGFR-Targeted TRAIL and a Smac Mimetic Synergize to Overcome Apoptosis Resistance in KRAS Mutant Colorectal Cancer Cells
por: Möller, Yvonne, et al.
Publicado: (2014)

Endothelin Signaling Mediates Biliary-Endothelial Crosstalk in Primary Sclerosing Cholangitis
por: Yin, Chunyue
Publicado: (2023)

CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis
por: Greenman, Raanan, et al.
Publicado: (2023)

Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic
por: Balakrishnan, Kumudha, et al.
Publicado: (2016)

Development and Characterization of Cholangioids from Normal and Diseased Human Cholangiocytes as an In Vitro Model to Study Primary Sclerosing Cholangitis
por: Loarca, Lorena, et al.
Publicado: (2017)

Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis
por: Mindikoglu, Ayse L, et al.
Publicado: (2019)

Cholestatic Pruritus Treatments in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: A Systematic Literature Review
por: Smith, Helen T., et al.
Publicado: (2023)

Distinct immune surveillance in primary biliary cholangitis and primary sclerosing cholangitis is linked with discrete cholangiocarcinoma risk
por: Nanjundappa, Roopa H., et al.
Publicado: (2023)

IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis
por: Tanaka, Atsushi
Publicado: (2019)

Redox regulation of Smac mimetic-induced cell death
por: Fulda, Simone
Publicado: (2015)

Smac-mimetics reduce numbers and viability of human osteoclasts
por: Moen, Ingrid Nyhus, et al.
Publicado: (2021)

Lymphocyte recruitment and homing to the liver in primary biliary cirrhosis and primary sclerosing cholangitis
por: Borchers, Andrea T., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_3gnotg73phtcf4ti6fmqauh1e6