Impaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a commonly pervasive inherited disease in many parts of the world. The complete lack of G6PD activity in a mouse model causes embryonic lethality. The G6PD-deficient Caenorhabditis elegans model also shows embryonic death as indicated by a sever...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Ling, Yang, Hung-Chi, Hung, Cheng-Yu, Ou, Meng-Hsin, Pan, Yi-Yun, Cheng, Mei-Ling, Stern, Arnold, Lo, Szecheng J, Chiu, Daniel Tsun-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386372/
https://www.ncbi.nlm.nih.gov/pubmed/28079896
http://dx.doi.org/10.1038/cddis.2016.463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386372/
https://www.ncbi.nlm.nih.gov/pubmed/28079896
http://dx.doi.org/10.1038/cddis.2016.463

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