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The TAZ–miR-224–SMAD4 axis promotes tumorigenesis in osteosarcoma

Transcriptional co-activator with PDZ-binding motif (TAZ) is a downstream effector of the Hippo signaling pathway that participates in tumorigenesis. The aim of this study was to identify the miRNA counterpart for TAZ and elucidate the mechanism underlying the tumorigenic effect of TAZ. We demonstra...

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Detalles Bibliográficos
Autores principales: Ma, Jianjun, Huang, Kangmao, Ma, Yan, Zhou, Menglu, Fan, Shunwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386375/
https://www.ncbi.nlm.nih.gov/pubmed/28055015
http://dx.doi.org/10.1038/cddis.2016.468