HIF-2α and Oct4 have synergistic effects on survival and myocardial repair of very small embryonic-like mesenchymal stem cells in infarcted hearts

Poor cell survival and limited functional benefits have restricted mesenchymal stem cell (MSC) efficacy for treating myocardial infarction (MI), suggesting that a better understanding of stem cell biology is needed. The transcription factor HIF-2α is an essential regulator of the transcriptional res...

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Detalles Bibliográficos
Autores principales: Zhang, Shaoheng, Zhao, Lan, Wang, Jiahong, Chen, Nannan, Yan, Jian, Pan, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386383/
https://www.ncbi.nlm.nih.gov/pubmed/28079892
http://dx.doi.org/10.1038/cddis.2016.480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386383/
https://www.ncbi.nlm.nih.gov/pubmed/28079892
http://dx.doi.org/10.1038/cddis.2016.480

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