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HIF-2α and Oct4 have synergistic effects on survival and myocardial repair of very small embryonic-like mesenchymal stem cells in infarcted hearts
Poor cell survival and limited functional benefits have restricted mesenchymal stem cell (MSC) efficacy for treating myocardial infarction (MI), suggesting that a better understanding of stem cell biology is needed. The transcription factor HIF-2α is an essential regulator of the transcriptional res...
Autores principales: | Zhang, Shaoheng, Zhao, Lan, Wang, Jiahong, Chen, Nannan, Yan, Jian, Pan, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386383/ https://www.ncbi.nlm.nih.gov/pubmed/28079892 http://dx.doi.org/10.1038/cddis.2016.480 |
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