Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress

Histological inspection of visually normal tissue adjacent to neoplastic lesions often reveals multiple foci of cellular abnormalities. This suggests the presence of a regional carcinogenic signal that spreads oncogenic transformation and field cancerization. We observed an abundance of mutagenic re...

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Detalles Bibliográficos
Autores principales: Chan, Jeremy Soon Kiat, Tan, Ming Jie, Sng, Ming Keat, Teo, Ziqiang, Phua, Terri, Choo, Chee Chong, LI, Liang, Zhu, Pengcheng, Tan, Nguan Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386391/
https://www.ncbi.nlm.nih.gov/pubmed/28102840
http://dx.doi.org/10.1038/cddis.2016.492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386391/
https://www.ncbi.nlm.nih.gov/pubmed/28102840
http://dx.doi.org/10.1038/cddis.2016.492

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