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MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2

MicroRNAs (miRNAs) have emerged as key players in cancer progression and metastatic initiation yet their importance in regulating prostate cancer (PCa) metastasis to bone has begun to be appreciated. We employed multimodal strategy based on in-house PCa clinical samples, publicly available TCGA coho...

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Detalles Bibliográficos
Autores principales: Colden, Melissa, Dar, Altaf A, Saini, Sharanjot, Dahiya, Priya V, Shahryari, Varahram, Yamamura, Soichiro, Tanaka, Yuichiro, Stein, Gary, Dahiya, Rajvir, Majid, Shahana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386393/
https://www.ncbi.nlm.nih.gov/pubmed/28125091
http://dx.doi.org/10.1038/cddis.2017.15