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MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2
MicroRNAs (miRNAs) have emerged as key players in cancer progression and metastatic initiation yet their importance in regulating prostate cancer (PCa) metastasis to bone has begun to be appreciated. We employed multimodal strategy based on in-house PCa clinical samples, publicly available TCGA coho...
Autores principales: | Colden, Melissa, Dar, Altaf A, Saini, Sharanjot, Dahiya, Priya V, Shahryari, Varahram, Yamamura, Soichiro, Tanaka, Yuichiro, Stein, Gary, Dahiya, Rajvir, Majid, Shahana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386393/ https://www.ncbi.nlm.nih.gov/pubmed/28125091 http://dx.doi.org/10.1038/cddis.2017.15 |
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