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Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model

Star-PAP is a noncanonical poly(A) polymerase and required for the expression of a select set of mRNAs. However, the pathological role of Star-PAP in cancer largely remains unknown. In this study, we observed decreased expression of Star-PAP in breast cancer cell lines and tissues. Ectopic Star-PAP...

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Detalles Bibliográficos
Autores principales: Yu, C, Gong, Y, Zhou, H, Wang, M, Kong, L, Liu, J, An, T, Zhu, H, Li, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386448/
https://www.ncbi.nlm.nih.gov/pubmed/28151486
http://dx.doi.org/10.1038/cddis.2016.199