Cargando…
Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model
Star-PAP is a noncanonical poly(A) polymerase and required for the expression of a select set of mRNAs. However, the pathological role of Star-PAP in cancer largely remains unknown. In this study, we observed decreased expression of Star-PAP in breast cancer cell lines and tissues. Ectopic Star-PAP...
Autores principales: | Yu, C, Gong, Y, Zhou, H, Wang, M, Kong, L, Liu, J, An, T, Zhu, H, Li, Y |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386448/ https://www.ncbi.nlm.nih.gov/pubmed/28151486 http://dx.doi.org/10.1038/cddis.2016.199 |
Ejemplares similares
-
Poly(A) polymerase (PAP) diversity in gene expression – Star-PAP vs canonical PAP
por: Laishram, Rakesh S.
Publicado: (2014) -
CKI isoforms α and ε regulate Star–PAP target messages by controlling Star–PAP poly(A) polymerase activity and phosphoinositide stimulation
por: Laishram, Rakesh S., et al.
Publicado: (2011) -
Star-PAP regulates tumor protein D52 through modulating miR-449a/34a in breast cancer
por: Duan, Aizhu, et al.
Publicado: (2019) -
The poly(A) polymerase PAPS1 mediates pollen maturation by regulating sperm cell differentiation in plants
por: Ali, Iftikhar, et al.
Publicado: (2022) -
Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association
por: Koshre, Ganesh R., et al.
Publicado: (2021)