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Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis

Preeclampsia, a serious hypertensive disorder of pregnancy, is characterized by elevated ceramide (CER) content that is responsible for heightened trophoblast cell death rates via apoptosis and autophagy. Whether trophoblast cells undergo necroptosis, a newly characterized form of regulated necrosis...

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Detalles Bibliográficos
Autores principales: Bailey, Liane Jennifer, Alahari, Sruthi, Tagliaferro, Andrea, Post, Martin, Caniggia, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386461/
https://www.ncbi.nlm.nih.gov/pubmed/28151467
http://dx.doi.org/10.1038/cddis.2016.483