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Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis
Preeclampsia, a serious hypertensive disorder of pregnancy, is characterized by elevated ceramide (CER) content that is responsible for heightened trophoblast cell death rates via apoptosis and autophagy. Whether trophoblast cells undergo necroptosis, a newly characterized form of regulated necrosis...
Autores principales: | Bailey, Liane Jennifer, Alahari, Sruthi, Tagliaferro, Andrea, Post, Martin, Caniggia, Isabella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386461/ https://www.ncbi.nlm.nih.gov/pubmed/28151467 http://dx.doi.org/10.1038/cddis.2016.483 |
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