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Oncogenic role of rab escort protein 1 through EGFR and STAT3 pathway

Rab escort protein-1 (REP1) is linked to choroideremia (CHM), an X-linked degenerative disorder caused by mutations of the gene encoding REP1 (CHM). REP1 mutant zebrafish showed excessive cell death throughout the body, including the eyes, indicating that REP1 is critical for cell survival, a hallma...

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Detalles Bibliográficos
Autores principales: Yun, Un-Jung, Sung, Jee Young, Park, Seog-Yun, Ye, Sang-Kyu, Shim, Jaegal, Lee, Jae-Seon, Hibi, Masahiko, Bae, Young-Ki, Kim, Yong-Nyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386492/
https://www.ncbi.nlm.nih.gov/pubmed/28230863
http://dx.doi.org/10.1038/cddis.2017.50