Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells

Dicer, a member of the RNase III family of endoribonucleases, has an important role in regulating methylation of CpG islands in mammal cancer cells. However, the underlying mechanism of action remains unclear. In this study, we demonstrated that upregulation of Dicer in cholangiocarcinoma (CCA) cell...

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Detalles Bibliográficos
Autores principales: Cheng, Wenlong, Qi, Yongqiang, Tian, Li, Wang, Bing, Huang, Wenhua, Chen, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386496/
https://www.ncbi.nlm.nih.gov/pubmed/28230864
http://dx.doi.org/10.1038/cddis.2017.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386496/
https://www.ncbi.nlm.nih.gov/pubmed/28230864
http://dx.doi.org/10.1038/cddis.2017.57

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