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Berbamine postconditioning protects the heart from ischemia/reperfusion injury through modulation of autophagy

Pretreatment of berbamine protects the heart from ischemia/reperfusion (I/R) injury. However it is unknown whether it has cardioprotection when given at the onset of reperfusion (postconditioning (PoC)), a protocol with more clinical impact. Autophagy is upregulated in I/R myocardium and exacerbates...

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Detalles Bibliográficos
Autores principales: Zheng, Yanjun, Gu, Shanshan, Li, Xuxia, Tan, Jiliang, Liu, Shenyan, Jiang, Yukun, Zhang, Caimei, Gao, Ling, Yang, Huang-Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386498/
https://www.ncbi.nlm.nih.gov/pubmed/28151484
http://dx.doi.org/10.1038/cddis.2017.7