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Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils

Periodontal disease is a prevalent chronic inflammatory condition characterised by an aberrant host response to a pathogenic plaque biofilm resulting in local tissue damage and frustrated healing that can result in tooth loss. Cysteine proteases (gingipains) from the key periodontal pathogen Porphyr...

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Detalles Bibliográficos
Autores principales: Castro, Sowmya A, Collighan, Russell, Lambert, Peter A, Dias, Irundika HK, Chauhan, Parbata, Bland, Charlotte E, Milic, Ivana, Milward, Michael R, Cooper, Paul R, Devitt, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386511/
https://www.ncbi.nlm.nih.gov/pubmed/28252646
http://dx.doi.org/10.1038/cddis.2016.481