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Immunoproteomic identification and characterization of Ni(2+)-regulated proteins implicates Ni(2+) in the induction of monocyte cell death

Nickel allergy is the most common cause of allergic reactions worldwide, with cutaneous and systemic effects potentially affecting multiple organs. Monocytes are precursors of not only macrophages but also dendritic cells, the most potent activators of nickel hypersensitivity. Monocytes are themselv...

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Detalles Bibliográficos
Autores principales: Jakob, Annika, Mussotter, Franz, Ohnesorge, Stefanie, Dietz, Lisa, Pardo, Julian, Haidl, Ian D, Thierse, Hermann-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386519/
https://www.ncbi.nlm.nih.gov/pubmed/28300831
http://dx.doi.org/10.1038/cddis.2017.112