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Molecular insights of Gas6/TAM in cancer development and therapy

Since growth arrest-specific gene 6 (Gas6) was discovered in 1988, numerous studies have highlighted the role of the Gas6 protein and its receptors Tyro3, Axl and Mer (collectively referred to as TAM), in proliferation, apoptosis, efferocytosis, leukocyte migration, sequestration and platelet aggreg...

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Detalles Bibliográficos
Autores principales: Wu, Guiling, Ma, Zhiqiang, Hu, Wei, Wang, Dongjin, Gong, Bing, Fan, Chongxi, Jiang, Shuai, Li, Tian, Gao, Jianyuan, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386520/
https://www.ncbi.nlm.nih.gov/pubmed/28333143
http://dx.doi.org/10.1038/cddis.2017.113