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Inhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain

Radiotherapy is an effective tool in the treatment of malignant brain tumors. However, damage to brain stem and progenitor cells constitutes a major problem and is associated with long-term side effects. Autophagy has been shown to be involved in cell death, and the purpose of this study was to eval...

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Detalles Bibliográficos
Autores principales: Wang, Yafeng, Zhou, Kai, Li, Tao, Xu, Yiran, Xie, Cuicui, Sun, Yanyan, Zhang, Yaodong, Rodriguez, Juan, Blomgren, Klas, Zhu, Changlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386526/
https://www.ncbi.nlm.nih.gov/pubmed/28333139
http://dx.doi.org/10.1038/cddis.2017.120