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TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis

The incomplete understanding of aberrant neovascularization, which contributes to osteoarthritis suggests that additional modulators have yet to be identified. Our objective was to identify the role of Leucine-rich-alpha-2-glycoprotein1 (LRG1), a new regulator of pathogenic angiogenesis, in osteoart...

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Detalles Bibliográficos
Autores principales: Wang, Yiyun, Xu, Jiajia, Zhang, Xudong, Wang, Chuandong, Huang, Yan, Dai, Kerong, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386532/
https://www.ncbi.nlm.nih.gov/pubmed/28358372
http://dx.doi.org/10.1038/cddis.2017.129