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The role of autophagy in asparaginase-induced immune suppression of macrophages

Erwinia asparaginase, a bacteria-derived enzyme drug, has been used in the treatment of various cancers, especially acute lymphoblastic leukemia (ALL). One of the most significant side effects associated with asparaginase administration is immune suppression, which limits its application in clinic....

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Detalles Bibliográficos
Autores principales: Song, Ping, Wang, Ziyu, Zhang, Xuyao, Fan, Jiajun, Li, Yubin, Chen, Qicheng, Wang, Shaofei, Liu, Peipei, Luan, Jingyun, Ye, Li, Ju, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386542/
https://www.ncbi.nlm.nih.gov/pubmed/28358370
http://dx.doi.org/10.1038/cddis.2017.144