Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response

Cancer cells are under chronic endoplasmic reticulum (ER) stress due to hypoxia, low levels of nutrients, and a high metabolic demand for proliferation. To survive, they constitutively activate the unfolded protein response (UPR). The inositol-requiring protein 1 (IRE1) and protein kinase RNA-like E...

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Detalles Bibliográficos
Autores principales: Taguchi, Yuki, Horiuchi, Yuta, Kano, Fumi, Murata, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386543/
https://www.ncbi.nlm.nih.gov/pubmed/28358375
http://dx.doi.org/10.1038/cddis.2017.147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386543/
https://www.ncbi.nlm.nih.gov/pubmed/28358375
http://dx.doi.org/10.1038/cddis.2017.147

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