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Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response

Cancer cells are under chronic endoplasmic reticulum (ER) stress due to hypoxia, low levels of nutrients, and a high metabolic demand for proliferation. To survive, they constitutively activate the unfolded protein response (UPR). The inositol-requiring protein 1 (IRE1) and protein kinase RNA-like E...

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Detalles Bibliográficos
Autores principales:	Taguchi, Yuki, Horiuchi, Yuta, Kano, Fumi, Murata, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386543/ https://www.ncbi.nlm.nih.gov/pubmed/28358375 http://dx.doi.org/10.1038/cddis.2017.147

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