Cargando…

Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres

The promyelocytic leukemia protein (PML) is expressed in most normal human tissues and forms nuclear bodies (NBs) that have roles in gene regulation and cellular processes such as DNA repair, cell cycle control, and cell fate decisions. Using murine C2C12 myoblasts, we demonstrate that activation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Salsman, Jayme, Rapkin, Lindsy M, Margam, Nandini N, Duncan, Roy, Bazett-Jones, David P, Dellaire, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386546/
https://www.ncbi.nlm.nih.gov/pubmed/28358373
http://dx.doi.org/10.1038/cddis.2017.151