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Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli

Commensal Escherichia coli has been identified as a major protagonist of microbe-induced colorectal oncogenesis. Its tumour-promoting attribute is linked to the expression of DNA-damaging genotoxins. Using a constitutively invasive variant of non-pathogenic E. coli, we demonstrate that chronic prese...

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Detalles Bibliográficos
Autores principales: Sahu, Upasana, Choudhury, Arnab, Parvez, Suhel, Biswas, Subhrajit, Kar, Sudeshna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386548/
https://www.ncbi.nlm.nih.gov/pubmed/28300841
http://dx.doi.org/10.1038/cddis.2017.27