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Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli
Commensal Escherichia coli has been identified as a major protagonist of microbe-induced colorectal oncogenesis. Its tumour-promoting attribute is linked to the expression of DNA-damaging genotoxins. Using a constitutively invasive variant of non-pathogenic E. coli, we demonstrate that chronic prese...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386548/ https://www.ncbi.nlm.nih.gov/pubmed/28300841 http://dx.doi.org/10.1038/cddis.2017.27 |