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The FOXM1–ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells

Paclitaxel is clinically used as a first-line chemotherapeutic regimen for several cancer types, including head and neck cancers. However, acquired drug resistance results in the failure of therapy, metastasis and relapse. The drug efflux mediated by ATP-binding cassette (ABC) transporters and the s...

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Detalles Bibliográficos
Autores principales: Hou, Youxiang, Zhu, Qianling, Li, Zheng, Peng, Yongbo, Yu, Xiaohui, Yuan, Bowen, Liu, Yijun, Liu, Youhong, Yin, Linglong, Peng, Yuchong, Jiang, Zhenghua, Li, Jinping, Xie, Bowen, Duan, Yumei, Tan, Guolin, Gulina, Kurban, Gong, Zhicheng, Sun, Lunquan, Fan, Xuegong, Li, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386553/
https://www.ncbi.nlm.nih.gov/pubmed/28277541
http://dx.doi.org/10.1038/cddis.2017.53