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Role for RIP1 in mediating necroptosis in experimental intracerebral hemorrhage model both in vivo and in vitro

Cell death is a hallmark of second brain injury after intracerebral hemorrhage (ICH); however, the mechanism still has not been fully illustrated. In this study, we explored whether necroptosis, a type of regulated necrosis, has an essential role in brain injury after ICH. We found that inhibiting r...

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Detalles Bibliográficos
Autores principales: Shen, Haitao, Liu, Chenglin, Zhang, Dongping, Yao, Xiyang, Zhang, Kai, Li, Haiying, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386555/
https://www.ncbi.nlm.nih.gov/pubmed/28252651
http://dx.doi.org/10.1038/cddis.2017.58