Cysteine-linked dimerization of BST-2 confers anoikis resistance to breast cancer cells by negating proapoptotic activities to promote tumor cell survival and growth

Almost all breast tumors express the antiviral protein BST-2 with 67%, 25% and 8.2% containing high, medium or low levels of BST-2, respectively. Breast tumor cells and tissues that contain elevated levels of BST-2 are highly aggressive. Suppression of BST-2 expression reprograms tumorigenic propert...

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Detalles Bibliográficos
Autores principales: Mahauad-Fernandez, Wadie D, Okeoma, Chioma M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386562/
https://www.ncbi.nlm.nih.gov/pubmed/28300825
http://dx.doi.org/10.1038/cddis.2017.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386562/
https://www.ncbi.nlm.nih.gov/pubmed/28300825
http://dx.doi.org/10.1038/cddis.2017.68

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