Mechanical compression induces VEGFA overexpression in breast cancer via DNMT3A-dependent miR-9 downregulation

Tumor growth generates mechanical compression, which may trigger mechanotransduction in cancer and stromal cells and promote tumor progression. However, very little is known about how compression stimulates signal transduction and contributes to tumor progression. In the present study, we demonstrat...

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Detalles Bibliográficos
Autores principales: Kim, Baek Gil, Gao, Ming-Qing, Kang, Suki, Choi, Yoon Pyo, Lee, Joo Hyun, Kim, Ji Eun, Han, Hyun Ho, Mun, Seong Gyeong, Cho, Nam Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386566/
https://www.ncbi.nlm.nih.gov/pubmed/28252641
http://dx.doi.org/10.1038/cddis.2017.73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386566/
https://www.ncbi.nlm.nih.gov/pubmed/28252641
http://dx.doi.org/10.1038/cddis.2017.73

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