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Mechanical compression induces VEGFA overexpression in breast cancer via DNMT3A-dependent miR-9 downregulation
Tumor growth generates mechanical compression, which may trigger mechanotransduction in cancer and stromal cells and promote tumor progression. However, very little is known about how compression stimulates signal transduction and contributes to tumor progression. In the present study, we demonstrat...
Autores principales: | Kim, Baek Gil, Gao, Ming-Qing, Kang, Suki, Choi, Yoon Pyo, Lee, Joo Hyun, Kim, Ji Eun, Han, Hyun Ho, Mun, Seong Gyeong, Cho, Nam Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386566/ https://www.ncbi.nlm.nih.gov/pubmed/28252641 http://dx.doi.org/10.1038/cddis.2017.73 |
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