MicroRNA-27a promotes podocyte injury via PPARγ-mediated β-catenin activation in diabetic nephropathy

Podocyte injury has a pivotal role in the pathogenesis of diabetic nephropathy (DN). MicroRNA-27a (miR-27a), peroxisome proliferator-activated receptor γ (PPARγ) and β-catenin pathways have been involved in the pathogenesis of DN. Herein, we asked whether miR-27a mediates podocyte injury through PPA...

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Detalles Bibliográficos
Autores principales: Zhou, Zhanmei, Wan, Jiao, Hou, Xiaoyan, Geng, Jian, Li, Xiao, Bai, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386567/
https://www.ncbi.nlm.nih.gov/pubmed/28277542
http://dx.doi.org/10.1038/cddis.2017.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386567/
https://www.ncbi.nlm.nih.gov/pubmed/28277542
http://dx.doi.org/10.1038/cddis.2017.74

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