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Bidirectional transcription of Linc00441 and RB1 via H3K27 modification-dependent way promotes hepatocellular carcinoma

The retinoblastoma gene (RB1), a known tumor-suppressor gene (TSG), was decreased in multiple cancers including hepatocellular carcinoma (HCC). Here we focused on the bidirectional transcripted long noncoding RNA (Linc00441) with neighbor gene RB1 to investigate whether Linc00441 is involved in the...

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Detalles Bibliográficos
Autores principales: Tang, Junwei, Xie, Yu, Xu, Xiaoliang, Yin, Yin, Jiang, Runqiu, Deng, Lei, Tan, Zhongming, Gangarapu, Venkatanarayana, Tang, Jinhai, Sun, Beicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386573/
https://www.ncbi.nlm.nih.gov/pubmed/28300839
http://dx.doi.org/10.1038/cddis.2017.81