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The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury

The mammalian target of rapamycin (mTOR) signal controls innate and adaptive immune response in multiple immunoregulatory contexts. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid cells of potent immunosuppressive capacity. In this study, we aimed to investigate th...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wang, Shuo, Li, Jiawei, Zhang, Weitao, Zheng, Long, Yang, Cheng, Zhu, Tongyu, Rong, Ruiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386577/
https://www.ncbi.nlm.nih.gov/pubmed/28333137
http://dx.doi.org/10.1038/cddis.2017.86