Cargando…

Aberrant iPSC-derived human astrocytes in Alzheimer's disease

The pathological potential of human astroglia in Alzheimer's disease (AD) was analysed in vitro using induced pluripotent stem cell (iPSC) technology. Here, we report development of a human iPSC-derived astrocyte model created from healthy individuals and patients with either early-onset famili...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, V C, Atkinson-Dell, R, Verkhratsky, A, Mohamet, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386580/
https://www.ncbi.nlm.nih.gov/pubmed/28333144
http://dx.doi.org/10.1038/cddis.2017.89