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Aberrant iPSC-derived human astrocytes in Alzheimer's disease
The pathological potential of human astroglia in Alzheimer's disease (AD) was analysed in vitro using induced pluripotent stem cell (iPSC) technology. Here, we report development of a human iPSC-derived astrocyte model created from healthy individuals and patients with either early-onset famili...
Autores principales: | Jones, V C, Atkinson-Dell, R, Verkhratsky, A, Mohamet, L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386580/ https://www.ncbi.nlm.nih.gov/pubmed/28333144 http://dx.doi.org/10.1038/cddis.2017.89 |
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