Scaffold-mediated gating of Cdc42 signalling flux

Scaffold proteins modulate signalling pathway activity spatially and temporally. In budding yeast, the scaffold Bem1 contributes to polarity axis establishment by regulating the GTPase Cdc42. Although different models have been proposed for Bem1 function, there is little direct evidence for an under...

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Detalles Bibliográficos
Autores principales: Rapali, Péter, Mitteau, Romain, Braun, Craig, Massoni-Laporte, Aurèlie, Ünlü, Caner, Bataille, Laure, Arramon, Floriane Saint, Gygi, Steven P, McCusker, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386590/
https://www.ncbi.nlm.nih.gov/pubmed/28304276
http://dx.doi.org/10.7554/eLife.25257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386590/
https://www.ncbi.nlm.nih.gov/pubmed/28304276
http://dx.doi.org/10.7554/eLife.25257

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