A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

Across many studies, animals with enhanced synaptic plasticity exhibit either enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can yield opposite learning outcomes? Here, we show that the recent history of experience can determine whether mice with enhanced plastic...

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Detalles Bibliográficos
Autores principales: Nguyen-Vu, TD Barbara, Zhao, Grace Q, Lahiri, Subhaneil, Kimpo, Rhea R, Lee, Hanmi, Ganguli, Surya, Shatz, Carla J, Raymond, Jennifer L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386593/
https://www.ncbi.nlm.nih.gov/pubmed/28234229
http://dx.doi.org/10.7554/eLife.20147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386593/
https://www.ncbi.nlm.nih.gov/pubmed/28234229
http://dx.doi.org/10.7554/eLife.20147

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