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A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity
Across many studies, animals with enhanced synaptic plasticity exhibit either enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can yield opposite learning outcomes? Here, we show that the recent history of experience can determine whether mice with enhanced plastic...
Autores principales: | Nguyen-Vu, TD Barbara, Zhao, Grace Q, Lahiri, Subhaneil, Kimpo, Rhea R, Lee, Hanmi, Ganguli, Surya, Shatz, Carla J, Raymond, Jennifer L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386593/ https://www.ncbi.nlm.nih.gov/pubmed/28234229 http://dx.doi.org/10.7554/eLife.20147 |
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