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Association of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients

BACKGROUND: The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate the influence of the PPP3CA c.249G>A variant on the clinical outcomes of kid...

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Detalles Bibliográficos
Autores principales: Salgado, Patricia C, Genvigir, Fabiana DV, Felipe, Claudia R, Tedesco-Silva, Helio, Medina-Pestana, Jose O, Doi, Sonia Q, Hirata, Mario H, Hirata, Rosario DC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386607/
https://www.ncbi.nlm.nih.gov/pubmed/28435308
http://dx.doi.org/10.2147/PGPM.S131390