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B7-H4 promotes tumor growth and metastatic progression in lung cancer by impacting cell proliferation and survival

Aberrant expression of B7-H4 occurs across a broad spectrum of human cancers. The aim of this study was to investigate the key role of B7-H4 during tumorigenesis and metastasis of human lung cancer. Our data showed that the shRNA-mediated disruption of B7-H4 markedly inhibited tumor cell proliferati...

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Detalles Bibliográficos
Autores principales: Zhang, Xiuqin, Cai, Liming, Zhang, Guangbo, Shen, Yu, Huang, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386653/
https://www.ncbi.nlm.nih.gov/pubmed/28061481
http://dx.doi.org/10.18632/oncotarget.14475