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Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents

Due to exposure to environmental toxicants, a “field cancerization” effect occurs in the lung resulting in the development of a field of initiated but morphologically normal appearing cells in the damaged epithelium of bronchial airways with dysregulated gene expression patterns. Using a mouse model...

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Detalles Bibliográficos
Autores principales: Xiong, Donghai, Pan, Jing, Zhang, Qi, Szabo, Eva, Miller, Mark Steven, Lubet, Ronald A., You, Ming, Wang, Yian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386655/
https://www.ncbi.nlm.nih.gov/pubmed/27935865
http://dx.doi.org/10.18632/oncotarget.13806