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The DNA repair function of CUX1 contributes to radioresistance

Ionizing radiation generates a broad spectrum of oxidative DNA lesions, including oxidized base products, abasic sites, single-strand breaks and double-strand breaks. The CUX1 protein was recently shown to function as an auxiliary factor that stimulates enzymatic activities of OGG1 through its CUT d...

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Detalles Bibliográficos
Autores principales: Ramdzan, Zubaidah M., Ginjala, Vasudeva, Pinder, Jordan B., Chung, Dudley, Donovan, Caroline M., Kaur, Simran, Leduy, Lam, Dellaire, Graham, Ganesan, Shridar, Nepveu, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386666/
https://www.ncbi.nlm.nih.gov/pubmed/28147323
http://dx.doi.org/10.18632/oncotarget.14875