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The DNA repair function of CUX1 contributes to radioresistance
Ionizing radiation generates a broad spectrum of oxidative DNA lesions, including oxidized base products, abasic sites, single-strand breaks and double-strand breaks. The CUX1 protein was recently shown to function as an auxiliary factor that stimulates enzymatic activities of OGG1 through its CUT d...
Autores principales: | Ramdzan, Zubaidah M., Ginjala, Vasudeva, Pinder, Jordan B., Chung, Dudley, Donovan, Caroline M., Kaur, Simran, Leduy, Lam, Dellaire, Graham, Ganesan, Shridar, Nepveu, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386666/ https://www.ncbi.nlm.nih.gov/pubmed/28147323 http://dx.doi.org/10.18632/oncotarget.14875 |
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