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High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models

Liver metastasis is the main cause of colon cancer-related death and is a recalcitrant disease. We report here the efficacy and safety of intra-portal-vein (iPV) targeting of Salmonella typhimurium A1-R on colon cancer liver metastasis in a nude-mouse orthotopic model. Nude mice with HT29 human colo...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Kei, Murakami, Takashi, Suetsugu, Atsushi, Kiyuna, Tasuku, Igarashi, Kentaro, Hiroshima, Yukihiko, Zhao, Ming, Zhang, Yong, Bouvet, Michael, Clary, Bryan M., Unno, Michiaki, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386670/
https://www.ncbi.nlm.nih.gov/pubmed/27683127
http://dx.doi.org/10.18632/oncotarget.12227