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Feedback circuitry via let-7c between lncRNA CCAT1 and c-Myc is involved in cigarette smoke extract-induced malignant transformation of HBE cells

Cigarette smoking is a primary risk factor for the development of lung cancer, which is regarded as the leading cause of cancer-related deaths. The process of malignant transformation of cells, however, is complex and elusive. The present study investigated the roles of an lncRNA, CCAT1, and a trans...

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Detalles Bibliográficos
Autores principales: Lu, Lu, Qi, Hong, Luo, Fei, Xu, Hui, Ling, Min, Qin, Yu, Yang, Ping, Liu, Xinlu, Yang, Qianlei, Xue, Junchao, Chen, Chao, Lu, Jiachun, Xiang, Quanyong, Liu, Qizhan, Bian, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386684/
https://www.ncbi.nlm.nih.gov/pubmed/28184029
http://dx.doi.org/10.18632/oncotarget.15195