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Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity

Heat-shock protein 90 (Hsp90), a highly conserved molecular chaperone, is frequently upregulated in tumors, and remains an attractive anti-cancer target. Hsp90 is also found extracellularly, particularly in tumor models. Although extracellular Hsp90 (eHsp90) action is not well defined, eHsp90 target...

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Detalles Bibliográficos
Autores principales: Nolan, Krystal D., Kaur, Jasmine, Isaacs, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386687/
https://www.ncbi.nlm.nih.gov/pubmed/28038472
http://dx.doi.org/10.18632/oncotarget.14252