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Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity
Heat-shock protein 90 (Hsp90), a highly conserved molecular chaperone, is frequently upregulated in tumors, and remains an attractive anti-cancer target. Hsp90 is also found extracellularly, particularly in tumor models. Although extracellular Hsp90 (eHsp90) action is not well defined, eHsp90 target...
Autores principales: | Nolan, Krystal D., Kaur, Jasmine, Isaacs, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386687/ https://www.ncbi.nlm.nih.gov/pubmed/28038472 http://dx.doi.org/10.18632/oncotarget.14252 |
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