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Targeting basal-like breast tumors with bromodomain and extraterminal domain (BET) and polo-like kinase inhibitors

Metastatic triple negative breast cancer (TNBC) is an incurable disease with limited therapeutic options, and no targeted therapies available. Triple negative tumors and the basal-like genomic subtype, are both characterized by a high proliferation rate and an increase in cell division. In this cont...

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Detalles Bibliográficos
Autores principales: Nieto-Jiménez, Cristina, Alcaraz-Sanabria, Ana, Pérez-Peña, Javier, Corrales-Sánchez, Verónica, Serrano-Heras, Gemma, Galán-Moya, Eva M., Serrano-Oviedo, Leticia, Montero, Juan Carlos, Burgos, Miguel, Llopis, Juan, Pandiella, Atanasio, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386699/
https://www.ncbi.nlm.nih.gov/pubmed/28061448
http://dx.doi.org/10.18632/oncotarget.14465