Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition

Bridging integrator-1 (Bin1), as a tumor suppressor, is frequently attenuated or even abolished in multiple primary cancers. A reduced expression of Bin1 caused by DNA methylation, has been reported in breast and prostate cancers. However, the methylation status of Bin1 and potent biological functio...

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Detalles Bibliográficos
Autores principales: Wang, Xuexiao, Wang, Jiali, Jia, Yunlong, Wang, Yu, Han, Xiaonan, Duan, Yuqing, Lv, Wei, Ma, Ming, Liu, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386712/
https://www.ncbi.nlm.nih.gov/pubmed/28152502
http://dx.doi.org/10.18632/oncotarget.14914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386712/
https://www.ncbi.nlm.nih.gov/pubmed/28152502
http://dx.doi.org/10.18632/oncotarget.14914

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