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Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

Tubulin-targeting molecules are widely used cancer therapeutic agents. They inhibit microtubule-based structures, including the mitotic spindle, ultimately preventing cell division. The final fates of microtubule-inhibited cells are however often heterogeneous and difficult to predict. While recent...

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Detalles Bibliográficos
Autores principales: Cesare, Erica Di, Verrico, Annalisa, Miele, Andrea, Giubettini, Maria, Rovella, Paola, Coluccia, Antonio, Famiglini, Valeria, Regina, Giuseppe La, Cundari, Enrico, Silvestri, Romano, Lavia, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386718/
https://www.ncbi.nlm.nih.gov/pubmed/28160569
http://dx.doi.org/10.18632/oncotarget.14980